BDBM26194 4-Hydroxybenzoate, III::4-hydroxybenzoic acid::CHEMBL441343::p-Hydroxybenzoic acid::phenol derivative, 8

SMILES OC(=O)c1ccc(O)cc1

InChI Key InChIKey=FJKROLUGYXJWQN-UHFFFAOYSA-N

Data  31 KI  7 IC50  1 EC50

PDB links: 63 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 26194   

TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM26194(4-Hydroxybenzoate, III | 4-hydroxybenzoic acid | C...)
Affinity DataKi:  920nMAssay Description:Inhibition of human CA1 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM26194(4-Hydroxybenzoate, III | 4-hydroxybenzoic acid | C...)
Affinity DataKi:  9.80E+3nMAssay Description:Inhibition of human carbonic anhydrase 1 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM26194(4-Hydroxybenzoate, III | 4-hydroxybenzoic acid | C...)
Affinity DataKi:  9.80E+3nM ΔG°:  -6.83kcal/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM26194(4-Hydroxybenzoate, III | 4-hydroxybenzoic acid | C...)
Affinity DataKi:  1.06E+6nM ΔG°:  -4.05kcal/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion using s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed